Parkinson's disease: Essential role in neuroinflammation found for a subset of brain macrophages

In Parkinson's disease, growing evidence targets neuroinflammation as essential for brain pathogenesis. But which group of immune cells that reside in the brain direct this inflammatory response? Scientists used a mouse model of Parkinson's disease to show that border-associated macrophages -- not microglia -- mediate the neuroinflammatory response in the brain.

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